ダメージのタイプ/マーカー |
サンプルタイプ |
細胞 |
組織 |
血液 |
尿 |
その他 |
DNA/RNA損傷 |
8-hydroxyguanosine(8-OHG) |
○ |
○ |
○ |
○ |
脳脊髄液 |
8-hydroxydeoxyguanosine(8-OHdG) |
○ |
○ |
○ |
○ |
|
8-Nitroguanine |
- |
- |
○ |
○ |
|
Abasic(AP) sites |
○ |
○ |
- |
- |
|
Aldehyde DNA Damage(Etheno adducts) |
○ |
○ |
- |
- |
|
BPDE DNA Adduct |
○ |
○ |
- |
- |
|
Comet Assay |
○ |
- |
- |
- |
|
Double-strand DNA breaks |
○ |
- |
- |
- |
|
UV DNA Damage(CPD and 6-4PP) |
○ |
- |
- |
- |
|
脂質過酸化反応 |
4-Hydroxynonenal(4-HNE) |
○ |
○ |
○ |
- |
|
Malondialdehyde(MDA) |
○ |
○ |
○ |
○ |
|
8-iso-Prostaglandin F2a(8-Isoprostane) |
○ |
○ |
○ |
○ |
|
Oxidized Low Density Lipoprotein(OxLDL) |
- |
- |
○ |
- |
|
タンパク質の酸化/ニトロ化 |
Protein carbonyl content(PCC) |
○ |
○ |
○ |
- |
|
3-Nitrotyrosine |
○ |
○ |
○ |
- |
|
Advanced Glycation End Products(AGE) |
○ |
○ |
○ |
- |
|
Advanced Oxidation Protein Products(AOPP) |
○ |
○ |
○ |
- |
|
BPDE Protein Adduct |
○ |
○ |
○ |
- |
|
CEL Protein Adducts |
○ |
○ |
○ |
- |
|
CEL Protein Adducts |
○ |
○ |
○ |
- |
|
CML Protein Adducts |
○ |
○ |
○ |
- |
|
Methylglyoxal Adducts |
○ |
○ |
○ |
- |
|
Protein Radicals |
○ |
○ |
○ |
- |
|
s-Glutathione Adducts |
○ |
○ |
○ |
- |
|
活性酵素種(ROS) |
|
|
|
|
|
Universal ROS |
○ |
○ |
○ |
○ |
|
Hydrogen Peroxide |
○ |
○ |
○ |
○ |
|
Nitric Oxide |
○ |
○ |
○ |
○ |
唾液 |
抗酸化物質 |
|
|
|
|
|
Catalase |
○ |
○ |
○ |
- |
|
Glutathione |
○ |
○ |
○ |
○ |
|
Superoxide Dismutase |
○ |
○ |
○ |
- |
|
Oxygen Radical Antioxidant Capacity(ORAC) |
○ |
○ |
○ |
○ |
食品 |
Hydroxyl Radical Antioxidant Capacity(HORAC) |
○ |
○ |
○ |
○ |
食品 |
Total Antioxidant Capacity(TAC) |
○ |
○ |
○ |
○ |
食品 |
Cell-Based Exogenous Antioxidant Assay |
- |
- |
- |
- |
食品、酸化防止剤 |